The review on: “Creutzfeldt-Jakob disease”

This review will explore the information about Creutzfeldt -Jakob disease (CJD), which is human prion disease. CJD a rare brain disorder and rapidly progressive. belongs to family of disease, caused by misfolded, transmissible infections particles, or prions. Transmissible spongiform encephalopathy (TSEs), also known as Spongiform refers characteristic appearance infected brains. affects one person in every million people per year worldwide. fatal neurodegenerative having higher mortality rate. usually appears later life has high incubation period but become progressive once clinically symptoms begin. exist three major groups sporadic (sCJD), Acquired CJD, Genetic CJD. The form generally late middle age elderly persons (Mean 67 years). Most with diagnosed die within year. Other illness like Alzheimer's involves deposition an aberrantly folded protein: although transmissible. There no specific treatment for except supportive care. arrangement different clinicians surveillance programs can maintain awareness control future incidence its transmission.